Various deletion mutants of Flag-tagged NOX5 or Pyk2 and HA-tagged NOX5 or Pyk2 were cloned into a pcDNA3

Various deletion mutants of Flag-tagged NOX5 or Pyk2 and HA-tagged NOX5 or Pyk2 were cloned into a pcDNA3.1 vector. poor prognosis. NOX5 induced the malignant progression of ESCC by activating Src, especially under hypoxic condition. Mechanistically, we showed that hypoxia promoted the interaction between NOX5 and Pyk2 on cell membrane via facilitating Ca2+-mediated Pyk2 Tyr402… Continue reading Various deletion mutants of Flag-tagged NOX5 or Pyk2 and HA-tagged NOX5 or Pyk2 were cloned into a pcDNA3