DHEA-treated rats tended to possess decreased urinary corticosterone to 11-dehydrocorticosterone ratios

DHEA-treated rats tended to possess decreased urinary corticosterone to 11-dehydrocorticosterone ratios. transcription of 11-HSD2 within a phosphatidylinositol-3 kinase/Akt-dependent way by increasing C/EBP- proteins and mRNA appearance. Moreover, it really is shown that C/EBP- and C/EBP- regulate the appearance of 11-HSD1 and 11-HSD2 differentially. To conclude, DHEA induces a change from 11-HSD1 to 11-HSD2 appearance, increasing… Continue reading DHEA-treated rats tended to possess decreased urinary corticosterone to 11-dehydrocorticosterone ratios